Lick a frog and get high

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Licking toads to get you high is a myth which appears to be reinforced in popular media, in shows like The Simpsons and Family Guy, the latter dedicating a whole episode to it. South Park even parodied this phenomenon writing an episode on if you get high from having a cat urinate in your face. But is there any truth behind it? Supposedly the cane toad secretes a chemical called 5-methoxy-N, N-dimethyltryptamine which can be sniffed, ingested or injected to make someone high. When the chemical gets into your body, it acts as an anti-depressant, releasing a high amount of serotonin into the body, making the user feel good.
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Toad Licking Trend

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Mythbusters: can you get high from licking toads? - The Courier Online

The Cane toad, which can grow to the size of a dinner plate, produces a toxin called bufotenine, which the toad secretes to ward off predators. When licked raw or cooked, the toxin acts as a hallucinogen. In the Southwest recently, several dogs have died after eating Cane toads, and the DEA has had bufotenine turn up at its research labs from time to time after drug arrests. The green-and-red toads produce the same toxin that is found in amanita mushrooms, cohoba seeds and other plants. South American Indians have used the toxin for years in religious ceremonies because of its mind-altering qualities, and some tribes have used it in blowguns to kill dinner.
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How Toad Licking Gets You High (And Then Kills You)

People do extreme things and could consume worse stuff than you can possibly imagine. One example of these extremes is toad licking. For strange reasons, toad licking is gradually becoming a serious phenomenon, especially in young people. These young people do this without paying attention to its harmful effects on health and lifestyle.
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Toad licking has long been recognized as a stupid, risky way to try to get high. But do you know the biochemistry that determines how stupid and risky it actually, and how high you could get. Let's squeeze some toads. The first problem with toad licking is that it isn't just any toad that will get you high.
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